Phosphatidylinositol 3 Kinase Pathway and 4-Hydroxy-2-Nonenal-Induced Oxidative Injury in the RPE
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منابع مشابه
Phosphatidylinositol 3 kinase pathway and 4-hydroxy-2-nonenal-induced oxidative injury in the RPE.
PURPOSE 4-Hydroxy-2-nonenal (4-HNE) is a major lipid peroxidation product in the retina and the retinal pigment epithelium. The purpose of the present study was to investigate how NF-E2-related factor-2 (Nrf2) and phosphatidylinositol 3 (PI3K) pathways affect the responses of cultured human retinal pigment epithelial (RPE) cells to 4-HNE. METHODS Cultured ARPE-19 cells were treated with diffe...
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ژورنال
عنوان ژورنال: Investigative Opthalmology & Visual Science
سال: 2009
ISSN: 1552-5783
DOI: 10.1167/iovs.08-2439